Nephrology Calculators & Kidney Function Tools
Evidence-based nephrology calculators for accurate kidney function assessment, CKD classification, and clinical decision support.
Why This Matters
Chronic kidney disease (CKD) affects approximately 10% of the global population, with prevalence increasing due to diabetes and hypertension. Accurate estimation of glomerular filtration rate (eGFR) and creatinine clearance (CrCl) is essential for CKD staging, drug dosing, and predicting renal outcomes. Early detection through these calculators can delay CKD progression and reduce cardiovascular risk.
When to Use
Use nephrology calculators when evaluating patients with diabetes, hypertension, or known kidney disease. eGFR (CKD-EPI or MDRD) for CKD screening and staging. CrCl (Cockcroft-Gault) for drug dosing. UACR for albuminuria assessment. FENa for differentiating prerenal vs intrinsic AKI.
Available Nephrology Calculators
eGFR (CKD-EPI)
The estimated glomerular filtration rate (eGFR) is a key indicator of kidney function calculated from serum creatinine. The CKD-EPI 2021 equation provides accurate estimation across all stages of kidney disease.
Calculate →CrCl / Renal Dosing
Creatinine Clearance (CrCl) estimated by the Cockcroft-Gault equation is the standard for renal drug dosing guidance in clinical practice.
Calculate →eGFR (MDRD)
The 4-variable MDRD (Modification of Diet in Renal Disease) Study equation estimates glomerular filtration rate from serum creatinine, age, sex, and race. It was developed from the MDRD Study and is widely validated in patients with chronic kidney disease.
Calculate →CrCl (Cockcroft-Gault)
The Cockcroft-Gault formula estimates creatinine clearance (CrCl) from serum creatinine, age, weight, and sex. It is the most widely used equation for medication dosing in renal impairment.
Calculate →FENa
The Fractional Excretion of Sodium (FENa) is a key diagnostic test in acute kidney injury (AKI) that helps differentiate prerenal azotemia from intrinsic renal failure. It measures the percentage of filtered sodium that is excreted in the urine.
Calculate →UACR
The Urine Albumin-to-Creatinine Ratio (UACR) is a key test for detecting albuminuria, a marker of kidney damage. It is used for CKD screening, staging, and monitoring. UACR is more accurate than a dipstick test and is the preferred method for quantifying albuminuria according to KDIGO guidelines.
Calculate →BUN/Cr Ratio
The BUN to creatinine ratio is a simple clinical tool used to differentiate between prerenal causes of acute kidney injury (dehydration, volume depletion, CHF, GI bleeding) and intrinsic renal causes.
Calculate →Kt/V
Kt/V is the standard measure of hemodialysis adequacy, quantifying the clearance of urea during a dialysis session. This calculator uses the Daugirdas formula for single-pool Kt/V (spKt/V) estimation.
Calculate →Schwartz eGFR
The Bedside Schwartz eGFR formula estimates glomerular filtration rate in children and adolescents aged 0-21 years using serum creatinine, height, age, and sex. It is the most widely used equation for pediatric kidney function assessment.
Calculate →AKI KDIGO Staging
The KDIGO AKI Staging system classifies acute kidney injury severity based on serum creatinine changes and urine output criteria, guiding clinical management and prognostication.
Calculate →
Clinical Guidelines
- KDIGO Clinical Practice Guideline for the Evaluation and Management of CKD (2024)
- KDIGO Clinical Practice Guideline for Diabetes Management in CKD (2024)
- NKF KDOQI Guidelines for Hemodialysis Adequacy (2023)
Frequently Asked Questions
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