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Infectious Disease Clinical Calculators & Assessment Tools

Evidence-based infectious disease calculators for bacteremia mortality risk (qPitt), systemic inflammation screening (SIRS Criteria), infective endocarditis diagnosis (Modified Duke Criteria), dengue severity classification (WHO 2009), and HIV clinical staging (WHO Staging).

Why This Matters

Infectious diseases remain a leading cause of morbidity and mortality worldwide. Gram-negative bacteremia carries a 10-30% mortality rate, making early risk stratification critical for appropriate triage and management. The SIRS criteria help identify patients with systemic inflammation who may have sepsis. Infective endocarditis has a 20-30% 1-year mortality, and the Modified Duke Criteria enable standardized diagnosis. Dengue affects 390 million people annually, and proper classification using WHO criteria reduces mortality from >20% to <1%. HIV/AIDS still affects 39 million people globally, and WHO clinical staging guides treatment decisions in resource-limited settings worldwide.

When to Use

Use qPitt for patients with Gram-negative bacteremia to assess 30-day mortality risk and guide ICU triage. Use SIRS Criteria for any patient with suspected infection or inflammation to screen for systemic inflammatory response. Use Modified Duke Criteria for patients with suspected infective endocarditis, especially those with fever + heart murmur + bacteremia. Use WHO Dengue Classification for patients with fever and clinical suspicion of dengue in endemic areas or returning travelers. Use WHO HIV Staging for HIV-positive patients to determine clinical stage and guide treatment initiation.

Our infectious disease calculators are developed in accordance with international guidelines including WHO, IDSA (Infectious Diseases Society of America), ESC (European Society of Cardiology), and WHO dengue and HIV guidelines.

Available Infectious Disease Calculators

Clinical Guidelines

  • IDSA Guidelines for Diagnosis and Management of Bacteremia (2024)
  • ESC Guidelines for Management of Infective Endocarditis (2023)
  • WHO Dengue Guidelines for Diagnosis and Management (2009)
  • WHO Consolidated Guidelines on Antiretroviral Drugs for HIV (2016)
  • Sepsis-3 Definitions — Singer et al. JAMA 2016
Enhance your infectious disease practice with Tabeeb+ clinic management software. Document qPitt, SIRS, Duke Criteria, dengue classification, and HIV stage in patient records with automated calculation.

Frequently Asked Questions

SIRS is systemic inflammation (≥2 criteria) from any cause, infectious or non-infectious. Sepsis is SIRS caused by infection PLUS organ dysfunction (per Sepsis-3: infection + SOFA ≥2). Septic shock is sepsis with persisting hypotension requiring vasopressors despite adequate fluid resuscitation and lactate >2 mmol/L.
qPitt is a simplified version using only 5 binary criteria without the 14-point mental status assessment of the full Pitt score. qPitt is faster to calculate at the bedside and has comparable predictive accuracy for 30-day mortality in Gram-negative bacteremia.
A "rejected" classification has high negative predictive value but does not completely exclude IE, especially in early disease or prosthetic valve endocarditis. If clinical suspicion remains high, repeat echocardiography and blood cultures are recommended.
Yes. While ART is now recommended for all HIV patients regardless of stage, WHO staging remains important for determining urgency of treatment, need for OI prophylaxis, and predicting prognosis. Stage 3-4 indicates advanced disease requiring urgent ART and close follow-up.

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Medical Disclaimer: This calculator is intended for use by healthcare professionals for educational and clinical decision support purposes only. It is not a substitute for professional clinical judgment.
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